Put ice on it! Do you experience a distinct tingling or prickling sensation in the area where a cold sore is about to emerge? If so, try applying ice on the area at the first sign of tingling. Some people find that this helps to relieve the pain of the outbreak. If your cold sore develops and it is especially painful or irritating, ask your doctor about using an anesthetic gel to lessen the pain. If you have repeated outbreaks, discuss with your doctor the possible benefits of taking an oral antiviral medication to help speed-up the healing process and minimize the chance of a recurrence.